Apathy in patients with Neuromyelitis Optica Spectrum Disorder.

ABSTRACT:

Background

Apathy is a common neuropsychiatric complication of neurological diseases, but it has not been investigated in patients with neuromyelitis optica spectrum disorders (NMOSD) until now.

Methods

We enrolled 66 patients diagnosed with NMOSD and assessed apathy using the self-reported version of the Apathy Evaluation Scale (AES-S). All the patients also completed the investigations composed of demographic data, disease characteristics, and composite evaluations of life status, including anxiety/depression, fatigue, sleep, and quality of life. Further statistical analysis proceeded.

Results

The mean AES-S score was 36.7 ± 8.3, with 40.9% of patients exhibiting clinically significant apathy (cutoff score: 36). Correlation analysis revealed that higher AES-S scores

SUBMITTER: He Z 

PROVIDER: S-EPMC12755817 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature