Factors associated with short-term recurrent ischemic stroke: culprit plaque, collateral circulation, and pathological mechanisms.

ABSTRACT:

Purpose

The purpose of the study was to investigate the predictive value of baseline plaque characteristics, perfusion injury, and pathological mechanisms for new ischemic cerebral lesions (NICLs) in medically treated patients with acute ischemic stroke (AIS) due to intracranial atherosclerotic stenosis (sICAS).

Methods

This was a retrospective analysis of AIS patients with 50-99% middle cerebral artery M1 segment (MCA-M1) stenosis undergoing high-resolution vessel wall magnetic resonance imaging (HR-VWI) and computed tomography perfusion (CTP) within 1 week of admission to evaluate plaque characteristics and collateral status (CS). sICAS pathogenesis was classified into three subtypes: artery-to-artery embolism (A-A), border zone infarction (BZI), and penetrating artery occ

SUBMITTER: Li G 

PROVIDER: S-EPMC12756096 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature