Soft drink consumption and liver fibrosis in type 2 diabetes.

ABSTRACT:

Introduction

Metabolic dysfunction-associated steatotic liver disease (MASLD) is highly prevalent among individuals with type 2 diabetes mellitus (T2DM), and liver fibrosis represents its strongest predictor of adverse outcomes. Soft drinks (SDs), a major source of added sugars and fructose, have been linked to metabolic disorders, but evidence on their relationship with liver fibrosis in patients with T2DM is limited. This study investigated the association between SDs consumption and liver fibrosis in adults with both T2DM and liver steatosis.

Methods

We analyzed 273 participants from the TESEO-DM cohort with imaging-documented hepatic steatosis (Controlled Attenuation Parameter, CAP ≥248 dB/m). SDs intake was assessed using the validated EPIC food frequency questionnaire

SUBMITTER: Ferro A 

PROVIDER: S-EPMC12756108 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature