Altered language-salience network connectivity in schizophrenia and differential associations with emotion regulation.

ABSTRACT:

Introduction

Emotion regulation is a key domain of social cognition, and its impairment contributes to poor psychosocial functioning in schizophrenia (SZ). The "Managing Emotions" (ME) branch of the Mayer-Salovey-Caruso Emotional Intelligence Test (MSCEIT) is widely used to assess this ability, yet its neural correlates remain unclear.

Methods

We examined resting-state functional connectivity (rsFC) associated with MSCEIT-ME performance in 56 patients with schizophrenia and 56 healthy controls matched for age, sex, and years of education. Seed-based correlation analyses focused on three large-scale networks previously implicated in emotion regulation: the salience network (SN), the language network (LN), and the ventral attention network (VAN). Between-group differences and

SUBMITTER: Biondi M 

PROVIDER: S-EPMC12756178 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature