High transmission risk in HIV-1 molecular transmission network among MSM is related to unsafe sexual behavior and adverse childhood experiences: a case-control study.

ABSTRACT:

Background

Molecular transmission networks enable successful identification of core transmitters compared to traditional epidemiological surveillance; however, behavioral characteristics and psychological drivers of these spreaders remain poorly characterized. Adverse childhood experiences (ACEs) are significantly more common among HIV-positive individuals than in the general population; yet empirical evidence showing that ACEs increase transmission risk among men who have sex with men (MSM) remains limited. This study investigates transmission risk in molecular network associations with sexual behaviors and adverse childhood experiences among MSM.

Methods

This study was a Case-Control Study based on molecular networks. A molecular transmission network was constructed using

SUBMITTER: Lin Z 

PROVIDER: S-EPMC12756416 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature