Descemet's membrane endothelial keratoplasty with scraping without descemetorhexis (DMEK-SWD) in a failed penetrating keratoplasty.

ABSTRACT:

Purpose

To introduce a novel treatment for a secondary failed penetrating keratoplasty (PK), termed Descemet's Membrane Endothelial Keratoplasty with endothelial scraping and without descemetorhexis (DMEK-SWD), through the presentation of two clinical cases.

Observations

In this prospective, single-center case series, two patients with previous PK for keratoconus developed endothelial decompensation, presenting with decreased visual acuity (Patient A: counting fingers; Patient B: 0.8 logMAR) and increased central corneal thickness (A: 735 μm; B: 653 μm). DMEK-SWD was performed using a 7.5-mm cell scraper through the temporal port to mechanically remove the host endothelium. A pre-stripped 7.5-mm DMEK graft was inserted using a standardized no-touch technique. Postoperative m

SUBMITTER: Wallace A 

PROVIDER: S-EPMC12756570 | biostudies-literature | 2026 Mar

REPOSITORIES: biostudies-literature