Prognostic Value of NT-proBNP in Patients Treated With Allogeneic Stem Cell Transplantation.

ABSTRACT:

Background

As survival rates after allogeneic stem cell transplantation (alloSCT) continue to grow, cardiovascular disease is becoming a major complication after alloSCT. However, the prognostic value of cardiac biomarkers has not been widely investigated.

Objectives

This study aims to investigate the association between baseline N-terminal prohormone of brain natriuretic peptide (NT-proBNP) in patients treated with alloSCT and mortality.

Methods

Patients who were referred for alloSCT between 2012 and 2023 were included in this single-center retrospective cohort study if NT-proBNP was measured <180 days before alloSCT. The primary study outcome was all-cause mortality and the secondary study outcome was a composite endpoint of major adverse cardiac events (acute coron

SUBMITTER: Polomski EAS 

PROVIDER: S-EPMC12756697 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature