Toward Cartilage-Mimicking Biomaterials: Biotribological, Biochemical and Structural Evaluation of pHEMA and PVA-Based Hydrogels.

ABSTRACT: This study compares the biotribological and structural behavior of PVA and pHEMA hydrogels under conditions simulating the cartilage environment to understand the lubrication mechanisms. PVA samples exhibited very low apparent friction coefficients and high-water uptake due to their hydrophilic, hydroxyl-rich network. In contrast, pHEMA hydrogels showed higher friction but substantially enhanced wear resistance, particularly under extended sliding against rough counterfaces. While PVA offers excellent lubrication performance, its wear stability remains limited. On the other hand, the low wear observed in pHEMAdespite its higher frictionsuggests strong structural resilience, making it a promising platform for further tailoring toward cartilage-mimicking applications. The results highlight

SUBMITTER: Necas D 

PROVIDER: S-EPMC12756760 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature