Silica Nanoparticles Block Natural Genetic Transformation in <i>Acinetobacter baylyi</i> ADP1.

ABSTRACT: The prolonged and widespread use of antibiotics has driven the emergence of resistance to many commonly employed drugs, posing a growing global challenge that requires urgent measures to curb its spread. Once resistance develops, horizontal gene transfer facilitates the exchange of genetic materials among various bacterial species, often preceding vertical transmission. Previous work to control horizontal gene transfer and specifically natural transformation within a population of bacteria approached the problem by addressing the bacterial mechanisms required for transformation. In this study, we investigated the possibility of controlling horizontal gene transfer by limiting access to or the availability of environmental DNA to the bacteria. In this study, we investigated the impact of fi

SUBMITTER: Adegoke SC 

PROVIDER: S-EPMC12756840 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature