Waiting to initiate venous thromboembolism prophylaxis increases the incidence of venous thromboembolism in pediatric patients with traumatic bleeding.

ABSTRACT:

Background

We aim to evaluate the relationship between timing of venous thromboembolism (VTE) prophylaxis initiation and incidence of VTE in a high-risk cohort of injured children.

Methods

This is a retrospective analysis of the Acute Care Surgery Trauma Quality Improvement Program database (2020-2022). Injured children (younger than 18 years) who received blood products or underwent hemorrhage control surgery within 4 hours of arrival were included. The primary outcome was VTE (deep venous thrombosis or pulmonary embolism). Multivariable analysis assessed the relationship between timing of VTE prophylaxis and VTE, adjusting for prophylaxis agent, type of surgery, head injury severity, interfacility transfer, total 4-hour blood product administration, injury mechanism, Injur

SUBMITTER: Feeney E 

PROVIDER: S-EPMC12756976 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature