Population attributable risk of a competing-risk model for breast cancer and non-breast cancer death among women ≥ 65 years.

ABSTRACT:

Purpose

To inform decision making around mammography-screening frequency and cessation, we previously used Fine-Gray competing-risk regression to develop and validate a model to estimate older women's 10-year risk of breast cancer and their competing risk of non-breast cancer (non-BC) death. Here, we aimed to understand the amount of incident breast cancer and non-BC death risk explained by our model among women ≥ 65y.

Methods

We included women ≥ 65y who completed the 2004 Nurses' Health Study questionnaire (NHS, n = 59,662) or who participated in the Women's Health Initiative-Extension Study (WHI-ES, n = 82,528). We calculated our model's full and risk factor-specific population attributable risk (PAR%) for incident breast cancer and non-BC death.

Results

Mean age of

SUBMITTER: Schonberg MA 

PROVIDER: S-EPMC12757117 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature