Differential prognostic value of high-sensitivity troponin T based on renal function status: insights from 14,208 ACS patients undergoing PCI.

ABSTRACT:

Background and objectives

High-sensitivity troponin T (hsTnT) is a standard biomarker for myocardial injury detection, but its prognostic value may differ by renal function status. This study evaluated how renal function modifies the prognostic significance of hsTnT in ACS patients undergoing PCI.

Methods

This study examined 14,208 acute coronary syndrome (ACS) patients who underwent percutaneous coronary intervention (PCI), stratified by renal function [estimated glomerular filtration rate (eGFR) < 60 vs. ≥60 mL/min/1.73 m²] and peak hsTnT levels [<5× vs. ≥5× upper reference limit (URL)]. Primary outcomes included one-year all-cause mortality and one-year incidence of ischemic events following the index PCI procedure.

Results

In patients with impaired rena

SUBMITTER: Na K 

PROVIDER: S-EPMC12757341 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature