Meta-analysis of global prevalence of hepatitis E virus infection in deer.

ABSTRACT:

Introduction

Hepatitis E virus (HEV) is an important zoonotic pathogen, and deer serve as a potential wildlife reservoir capable of contributing to human infections through wildlife-livestock-human transmission pathways. Accurate estimates of HEV prevalence in deer are essential for understanding zoonotic risks and informing surveillance strategies.

Methods

We conducted a systematic search across five major databases. Among 134 publications screened, 33 studies met the inclusion criteria for meta-analysis. Pooled prevalence estimates were calculated, and subgroup analyses were performed by region, development status, time period, age, sex, and diagnostic method. Serological assays (ELISA) and molecular assays (RT-PCR and RT-qPCR) were evaluated separately.

Results

Sig

SUBMITTER: Gao ZQ 

PROVIDER: S-EPMC12757369 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature