Body site-specific micro- and lactobiota in genitourinary infections during pregnancy.

ABSTRACT:

Background

Immunological, metabolic, and hormonal changes occur during pregnancy, which can affect the composition and function of the microbiota in diverse body sites. These changes can influence pregnancy outcomes and the health of the mother and baby. We aimed to characterize the microbiota of pregnant women across various body sites and examine the clinical and population-specific factors associated with its composition. The role of lactobacilli in genitourinary infections during pregnancy was analyzed as well.

Material and methods

One hundred and five pregnant women with gestational age between 15 and 20 weeks were recruited from the Women's Clinic of Tartu University Hospital, Estonia. Microbiota samples of the cervix (C, n = 84), vagina (V, n = 85), urin

SUBMITTER: Koljalg S 

PROVIDER: S-EPMC12757402 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature