Antenatal ultrasound diagnosis of fetal micrognathia: validation and reproducibility of quantitative methods.

ABSTRACT:

Objectives

The antenatal ultrasound diagnosis of fetal micrognathia can be made subjectively or objectively. We aimed to validate quantitative ultrasound methods proposed for the diagnosis of fetal micrognathia in the second and third trimesters of pregnancy by evaluating their diagnostic performance, reproducibility and impact of measurement variability on diagnosis.

Methods

This was a retrospective study analyzing the objective diagnostic accuracy, reproducibility and impact of measurement variability of mandible angle measurements from facial profile images of fetuses with suspected micrognathia diagnosed antenatally using a subjective method. Fetuses were recruited at between 18 and 28 weeks' gestation, at University College London Hospital, UK, between 2000 and 2018. Fo

SUBMITTER: Denk MC 

PROVIDER: S-EPMC12757816 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature