Combination of laser-generated silicon NPs and electrospun-nanofibres for the development of new-generation bioactive wound dressings.

ABSTRACT: The fabrication of wound dressings able to promote and accelerate healing is a key challenge to manage a variety of complex wounds including chronic disease or traumatic wounds. In this context, electrospun-nanofibrous scaffolds involving bioactive nanoparticles (NPs) appear as a very promising approach, which was investigated in the present work. We report the fabrication and evaluation of novel bioactive wound dressings associating electrospun ε-polycaprolactone (PCL) imbricated nanofibers (NFs) and laser-synthesized silicon NPs (SiNPs) obtained from green, impurity-free physical routes. A successful protocol of PCL NFs preparation and functionalization with SiNPs was achieved in aqueous acidic solution in the presence of aminopropyltriethoxysilane (APTES). We demonstrated this proof of

SUBMITTER: Scarabelli R 

PROVIDER: S-EPMC12757934 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature