Impact of Patent Foramen Ovale on In-Hospital Outcomes in Acute Pulmonary Embolism.

ABSTRACT:

Background

Patent foramen ovale (PFO) may complicate acute pulmonary embolism (PE) by enabling paradoxical embolism, but its clinical impact remains unclear. We evaluated the characteristics, management, and outcomes of patients hospitalized with PE with or without PFO.

Methods

Using the National Inpatient Sample database, adult patients admitted with acute PE between 2016 and 2020 were identified via ICD-10 codes. Patients were grouped based on whether they had concomitant PFO. Clinical characteristics, advanced therapies, and in-hospital outcomes were compared between patients with and without PFO. Multivariable logistic regression analyses were adjusted for demographics and comorbidities, with outcomes reported as adjusted odds ratios (aORs) and 95% confidence intervals (

SUBMITTER: Jabri A 

PROVIDER: S-EPMC12758048 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature