Effects of Daily Ambient Temperature on Intraocular Pressure: A Time-Series Analysis Using Generalized Additive and Distributed Lag Nonlinear Models.

ABSTRACT:

Purpose

The purpose of this study was to investigate the potential nonlinear association between ambient temperature and intraocular pressure (IOP), as well as the short- to medium-term lagged effects of temperature exposure on IOP.

Methods

A time-series study was conducted using 2018 to 2023 outpatient data from Shimane University Hospital in Izumo, Japan. Daily meteorological data were obtained from the Japan Meteorological Agency. We analyzed the association between ambient temperature and IOP using generalized additive models (GAMs) to assess nonlinearity, and distributed lag nonlinear models (DLNMs) to evaluate cumulative lag-effects. The main model was adjusted for time-related confounders (timeline, day of the week, public holidays, and season).

Results

We anal

SUBMITTER: Yoshida Y 

PROVIDER: S-EPMC12758437 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature