Uric acid levels mediate the association between four dietary indices and kidney stones in US adults: A cross-sectional study of NHANES 2007-2018.

ABSTRACT:

Background

Diet and uric acid are closely linked to the formation of kidney stones. However, the specific dietary indices associated with kidney stone risk and the mediating role of uric acid remain unclear. This study investigates the association between four dietary indices and kidney stone risk while exploring the mediating role of uric acid.

Methods

Data were obtained from the National Health and Nutrition Examination Survey (NHANES). Four dietary indices were calculated: the Mediterranean Diet (MED), Healthy Eating Index-2020 (HEI-2020), Alternate Healthy Eating Index (AHEI), and Dietary Approaches to Stop Hypertension (DASH). Univariate logistic regression analysis and restricted cubic splines (RCS) curve were used to analyze the single effect of dietary index and kidn

SUBMITTER: Cao J 

PROVIDER: S-EPMC12758690 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature