Chinmo function in cockroaches provides new insights into the regulation and evolution of insect metamorphosis.

ABSTRACT: Insect metamorphosis occurs in two main forms, hemimetaboly (simple) and holometaboly (complete), both regulated by hormonal and genetic pathways involving the transcription factors Krüppel homolog 1 (Kr-h1), Broad-Complex (BR-C), and Ecdysone-induced protein 93F (E93). The BTB-zinc finger protein Chronologically inappropriate morphogenesis (Chinmo), recently identified in the fruit fly Drosophila melanogaster, an holometabolan, as a larval state maintainer, was studied here in the German cockroach, Blattella germanica, an hemimetabolan. We also examined another BTB transcription factor, Abrupt (Ab), based on findings in another holometabolan, the red flour beetle, Tribolium castaneum, suggesting a cooperative role. We characterized chinmo expression in B. germanica and found sustained tra

SUBMITTER: Escudero J 

PROVIDER: S-EPMC12758806 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature