Descriptives and Genetic Correlates of Eating Disorder Diagnostic Transitions and Presumed Remission in the Danish Registry.

ABSTRACT:

Background

Eating disorders (EDs) are serious psychiatric disorders with an estimated 3.3 million healthy life-years lost worldwide yearly. Understanding the course of illness, diagnostic transitions and remission, and their associated genetic correlates could inform both ED etiology and treatment. We investigated occurrences of ED transitions and presumed remission and their genetic correlates as captured by polygenic scores (PGSs) in a large Danish register-based cohort.

Methods

The sample comprised 10,565 individuals with a diagnosis of anorexia nervosa (AN), bulimia nervosa (BN), or eating disorder not otherwise specified (EDNOS) and with at least two registered hospital contacts between 1995 and 2018. Based on medical records, the occurrence of diagnostic transitions an

SUBMITTER: Abdulkadir M 

PROVIDER: S-EPMC12759185 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature