Impact of frailty on outcomes of inpatient stereotactic radiosurgery for brain metastasis: a national readmission database analysis 2016-2020.

ABSTRACT:

Background

It is not clear how frailty may affect the outcomes of stereotactic radiosurgery (SRS) for brain metastasis. This study aimed to evaluate the impact of frailty on clinical outcomes in patients ≥ 60 years old who underwent SRS for brain metastasis from a population-based perspective.

Materials and methods

Data were extracted from the National Readmission Database (NRD), 2016 to 2020. Inclusion criteria were ≥ 60 years old with brain metastasis who underwent SRS. Frailty was assessed using the modified Frailty Index (mFI), derived from 11 clinical conditions. The primary outcomes were in-hospital mortality, length of hospital stay (LOS), total hospital costs, and 30-day and 90-day readmission rates. Logistic and linear regression models were used to assess the assoc

SUBMITTER: Chan RWY 

PROVIDER: S-EPMC12763895 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature