Clinical characteristics and outcome of fetuses with ventriculomegaly: a retrospective multicenter study.

ABSTRACT:

Purpose

To evaluate the incidence of associated structural anomalies, chromosomal/genetic abnormalities, infections and outcomes of fetuses with ventriculomegaly (VM).

Methods

Retrospective multicenter cohort study of 627 pregnancies with fetal VM. VM was classified as mild, moderate, or severe and isolated or non-isolated. Genetic, obstetric and outcome data were collected and compared according to VM categories.

Results

The incidences of associated structural anomalies were 21.9%, 53.1% and 63.9% in mild, moderate and severe VM, respectively (p = 0.032 mild vs. moderate-severe). The incidences of genetic abnormality and fetal infection of the total VM group were 16.1% and 0.8%, respectively, with no significant differences between the VM categories (p > 0.05). The i

SUBMITTER: Davutoglu EA 

PROVIDER: S-EPMC12764503 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature