More severe natural course of Crohn's disease in Yunnan province compared with Asian and Western countries.

ABSTRACT:

Background

Most patients with Crohn's disease (CD) experience disease progression and will eventually undergo surgery. However, the risks of progression and surgery exhibit significant regional heterogeneity. We conducted a cohort study to explore the risks and associated factors for disease progression, surgery, and postoperative recurrence in CD patients from Yunnan, a plateau province in southwestern China, and compared these data with data from Asian and Western countries.

Methods

In this study, data from a multicentre cohort from Yunnan Province were collected and analyzed. The cumulative risks of disease progression, surgery, and postoperative recurrence were analyzed. Univariate and multivariate analyses were performed to explore the independent risk factors associate

SUBMITTER: Tao Y 

PROVIDER: S-EPMC12764540 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature