Length of hospital stay and outcome in primary central nervous system lymphoma: a French retrospective multicentric study.

ABSTRACT: Primary central nervous system lymphoma (PCNSL) is a rare form of lymphoma with a poor prognosis. We used the LOC network database, including 365 patients from 14 voluntary centers. Inclusion criteria were age ≥ 60 years, immunocompetence, confirmed PCNSL diagnosis and treatment with curative intent with MPV-based regimen (Methotrexate, Procarbazine, Vincristine) between 2011 and 2021. We analyzed LOS from first day of chemotherapy to dismissal from hospital. Using the MAXStat method we found the LOS threshold of 15 days, to be one of most statistically significant and most convenient to separate two groups with different OS. The median age of the whole population was 71 years, median Karnofsky performance score (KPS) was 70%. The main differences between short and long LOS groups were med

SUBMITTER: Maguet R 

PROVIDER: S-EPMC12764697 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature