A network meta-analysis on the optimal treatment of malignant gastric outlet obstruction.

ABSTRACT:

Background

Gastric outlet obstruction (GOO) caused by malignancy significantly impairs patient quality of life. Surgical gastrojejunostomy (SGJ), endoscopic stenting (ES), and endoscopic ultrasound-guided gastroenterostomy (EUS-GE) are the three main palliative treatments. However, the optimal approach remains unclear because of variations in study results and limited studies comparing treatment types.

Objectives

To evaluate and compare the effectiveness and safety of EUS-GE, ES, and SGJ in the management of GOO.

Design

Network meta-analysis.

Data sources and methods

The PubMed, Cochrane Library, and Web of Science databases were systematically searched for full-length articles of randomized controlled trials and cohort studies in English comparing SGJ, ES, and

SUBMITTER: Tamura T 

PROVIDER: S-EPMC12764756 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature