A novel predictor of short-term prognosis in acute pulmonary embolism: inflammatory burden index.

ABSTRACT:

Background

Inflammation significantly impacts disease progression and prognosis in acute pulmonary embolism (APE); however, the optimal method to quantify this inflammation for prognostic purposes remains unclear.

Objectives

We aimed to identify the most effective blood-based inflammatory marker for predicting short-term mortality in patients with APE.

Methods

We retrospectively analyzed 301 patients with APE. We compared the predictive performance of nine inflammatory markers for 30-day mortality, focusing on the inflammatory burden index (IBI), and contrasted it with the standard clinical score (sPESI).

Results

After adjusting for potential confounders, a higher IBI was strongly and independently associated with an increased risk of 30-day mortality. IBI demo

SUBMITTER: Huang L 

PROVIDER: S-EPMC12764757 | biostudies-literature | 2026 Jan-Dec

REPOSITORIES: biostudies-literature