Responses to active stand test predict 12-year incident cardiovascular disease and mortality.

ABSTRACT:

Background

An integrated haemodynamic response during standing may serve as a marker of neuro-cardiovascular function. Individual components of both heart rate (HR) and blood pressure (BP) responses to active stand (AS) have been linked with cardiovascular disease (CVD) and mortality. We hypothesised that integrating BP/HR information from the entire haemodynamic response curve may uncover otherwise unknown associations with both CVD and mortality.

Methods

Beat-to-beat measurements of dynamic HR/BP responses to AS were conducted in 4336 individuals (61.5 ± 8.2 years; 53.7% female). We assessed longitudinal associations between entire HR/BP response curves during AS, incident CVD and mortality over 12 years, and cross-sectional association with CVD on an independent clinical

SUBMITTER: Hernandez B 

PROVIDER: S-EPMC12764857 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature