Antigenic and genotypic relatedness of buffalo-derived <i>Theileria parva</i> from Zambia to cattle-derived parasites and vaccine stocks.

ABSTRACT: The African buffalo (Syncerus caffer) is the natural reservoir of Theileria parva, a tick-transmitted protozoan parasite that severely constrains cattle production across eastern, southern, and central Africa. While the antigenic and genetic diversity of cattle-derived T. parva (causing East Coast fever) is well characterized in Zambia, little is known about the buffalo-derived parasites. The latter cause the equally fatal Corridor disease and impact the epidemiology and control of bovine theileriosis, particularly where live vaccines are used. This study investigated antigenic and genotypic diversity of T. parva from three Zambian buffalo populations, in comparison with cattle-derived parasites and vaccine stocks (Katete and Chitongo). Analysis of Tp1 and Tp2 a

SUBMITTER: Choopa CN 

PROVIDER: S-EPMC12765116 | biostudies-literature | 2026 Apr

REPOSITORIES: biostudies-literature