Associations between dietary patterns and the incidence of idiopathic pulmonary fibrosis: A cohort study.

ABSTRACT:

Background

Idiopathic pulmonary fibrosis (IPF) is a progressive, age-related lung disease with few modifiable risk factors. While healthy dietary patterns have been associated with reduced risk of chronic diseases, their impact on IPF remains unclear. This study investigated the relationship between adherence to healthy dietary patterns and incident IPF and explored whether phenotypic age acceleration mediates this association.

Methods

We analyzed 196,473 participants from the UK Biobank. Dietary intake was assessed via repeated 24 -h recall questionnaires, and adherence scores were calculated for the DASH, MEDAS, and MIND dietary patterns. Cox proportional hazards models were used to estimate the association between dietary scores and incident IPF. Mediation analysis was co

SUBMITTER: Li Y 

PROVIDER: S-EPMC12765324 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature