Inspecting the association between metabolic obese phenotypes and heart failure subtypes risk.

ABSTRACT:

Aim

Obesity and metabolic unhealth don't always co-exist. The relation between phenotypes derived from metabolic obese status and heart failure (HF) subtypes categorized by left ventricular ejection fraction (LVEF) is unclear. We aimed to investigate the association between metabolic obese phenotypes and future HF subtypes risk.

Objectives

A total of 9791 participants from the ARIC study were classified into phenotypes based on obese and metabolic status: metabolically healthy non-obesity (MHNO), metabolically healthy obesity (MHO), metabolically unhealthy non-obesity (MUNO) and metabolically unhealthy obesity (MUO).

Methods

Cox regression models were applied to explore the relationship between metabolic obese phenotypes and risk of HF with preserved ejection fraction

SUBMITTER: Zhang J 

PROVIDER: S-EPMC12765338 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature