Trends in local, regional and contralateral breast tumor recurrence within five years after diagnosis in the Netherlands: a population-based study including 121347 patients.

ABSTRACT:

Background

The objective was to provide an overview of trends in five-year local recurrence (LR), regional recurrence (RR) and contralateral breast cancer (CBC) rates in the Netherlands from 2003 to 2008 and 2012-2016.

Methods

Women ≥18 years diagnosed with primary early breast cancer between 2003-2008 and 2012-2016 in the Netherlands were included. LR was defined as invasive tumor on the same side as the primary breast cancer. RR was defined as regional lymph node metastasis. CBC was defined as second primary invasive breast tumor in the contralateral breast. Five-year LR, RR and CBC rates were calculated and stratified for age, stage, subtype, and grade.

Results

Of the 121347 included patients, 5618 were diagnosed with a LR, RR or CBC. Five-year LR, RR and CBC rates

SUBMITTER: Meijer J 

PROVIDER: S-EPMC12765441 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature