Prognostic significance of beta-adrenergic receptor expression in oesophageal adenocarcinoma.

ABSTRACT: Expression of the β-adrenergic receptors' family has been associated with survival outcomes in multiple different cancer types, showing their potential to act as prognostic factors. No previous work has evaluated these receptors in relation to survival in oesophageal adenocarcinoma. We sought to analyse the expression of β₁ and β₂ adrenergic receptors in oesophageal adenocarcinoma and their association with survival outcomes. The expression of β₁ and β₂ adrenergic receptors was evaluated in a cohort of oesophageal adenocarcinoma patients treated with neo-adjuvant chemotherapy prior to surgical resection at the Northern Ireland Cancer Centre between 2004 and 2012. Immunohistochemical staining for was assessed using a Tissue Microarray with triplic

SUBMITTER: Oliveira T 

PROVIDER: S-EPMC12765628 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature