Discovery of mannose as an alternative non-nutrient-deficient regulator of lipid accumulation in microalgae.

ABSTRACT:

Introduction

Microalgae are considered promising bioenergy producers, but their commercial potential is limited by low lipid yields. Nutrient deprivation, particularly nitrogen starvation, is a primary strategy to enhance lipid synthesis efficiency in microalgae. However, controlling this process flexibly, effectively, and accurately remains challenging. Moreover, nutrient deficiency triggers expression changes of numerous genes, complicating the identification of key lipid biosynthesis regulators.

Objectives

For the first time, we investigated mannose as a novel non-nutrient-deficient regulator of lipid accumulation in microalgae and explored its potential underlying mechanisms.

Methods

We examined how mannose induction affectslipid accumulation in Chlorella sorokini

SUBMITTER: Liu P 

PROVIDER: S-EPMC12766222 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature