Magnetic dipole imaging of magnetite nanoparticles in brain tissue.

ABSTRACT: The human brain contains magnetic iron oxide nanoparticles in the form of magnetite (Fe₃O₄); however, the origin and physiological implications of these crystals remain debated. Due to their low concentrations in brain tissue (∼1-20 ng g^-1), the identification and characterization of individual magnetic particles require nanometer-scale spatial resolution over large scan volumes. In contrast to conventional electron microscopy techniques that have field of views typically on micron scales, the Quantum Diamond Microscope (QDM), based on wide-field nitrogen-vacancy center imaging, can generate magnetic field maps over areas of several square millimeters while detecting nanoscale particles. Moreover, the QDM can directly quantify the strength and direction of

SUBMITTER: Kaub L 

PROVIDER: S-EPMC12766265 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature