Preoperative magnetic resonance imaging-based radiomics nomogram model for predicting postoperative anastomotic leakage in colorectal cancer.

ABSTRACT:

Purpose

Anastomotic leakage (AL) is a serious postoperative complication after colorectal cancer surgery, and accurate preoperative prediction remains challenging. This study aimed to develop and validate a magnetic resonance imaging (MRI)-based radiomics nomogram for the preoperative prediction of AL.

Methods

A total of 146 patients with colorectal cancer, including 11 with AL, were retrospectively enrolled and randomly divided into training and validation cohorts at a 7:3 ratio. Clinical variables and preoperative MRI-based radiomic features were analyzed. A clinical model was constructed using logistic regression. Radiomic features were selected using the least absolute shrinkage and selection operator method to develop a radiomics model, from which a radiomic score was c

SUBMITTER: Yan J 

PROVIDER: S-EPMC12766395 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature