Frailty and long-term outcomes in younger patients with acute myocardial infarction.

ABSTRACT:

Background and aims

Frailty is increasingly recognized as an important determinant of adverse outcomes in older adults with acute myocardial infarction (AMI), but its impact in younger patients remains underexplored. The aims of this study were to evaluate the association of frailty with adverse outcomes in AMI patients, stratified by age.

Methods

This population-based epidemiological study utilized linked national administrative data from England and Wales. Patients were stratified into three age groups: <55 years, 55-74 years, and ≥75 years. Frailty was assessed using the Secondary Care Administrative Records Frailty index with patients categorized into fit, mild, moderate, and severe groups. All-cause mortality at 1 year was the primary outcome. Secondary outcomes were ca

SUBMITTER: Mohiaddin H 

PROVIDER: S-EPMC12766437 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature