Simultaneous free-breathing T1, T2, and T1ρ mapping for myocardial fibrosis detection in non-ischemic cardiomyopathy: A comparative study with conventional techniques.

ABSTRACT:

Background

Quantitative myocardial mapping is critical for tissue characterization in non-ischemic cardiomyopathy (NICM). However, conventional techniques require separate breath-hold acquisitions, prolonging scan time and impairing co-registration. This study aimed to assess the feasibility and diagnostic performance of a novel free-breathing multimap (FBmultimap) sequence enabling simultaneous T1, T2, and T1ρ mapping in a single acquisition.

Methods

Onehundred-nine participants were prospectively enrolled, including 48 with hypertrophic cardiomyopathy (HCM), 28 with dilated cardiomyopathy (DCM), and 33 healthy controls. All underwent cardiac MRI with both FBmultimap and conventional mapping sequences (modified Look-Locker inversion recovery (MOLLI) T1, T2-prepared balanced

SUBMITTER: Wu Y 

PROVIDER: S-EPMC12766603 | biostudies-literature | 2025 Winter

REPOSITORIES: biostudies-literature