Differences and contributors to global cognitive performance in the underrepresented Latinx Parkinson's disease population.

ABSTRACT: Objective: Despite significant progress in understanding the factors influencing cognitive function in Parkinson's disease (PD), there is a notable gap in data representation for the Latinx population. This study aims to evaluate the contributors to and disparities in cognitive performance among Latinx patients with PD. Methods: A retrospective analysis was conducted based on cross-sectional data encompassing demographic, environmental, motor, and non-motor disease characteristics from the Latin American Research Consortium on the Genetics of PD (LARGE-PD) and the Parkinson's Progression Markers Initiative (PPMI) cohorts. Linear regression multivariable models were applied to identify variables affecting Montreal Cognitive Assessment (MoCA) scores, accounting for age, sex, an

SUBMITTER: Anis S 

PROVIDER: S-EPMC12766622 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature