Risk factors for hyperuricaemia-hypertension comorbidity in Chinese children and adolescents: a protocol for systematic review and meta-analysis.

ABSTRACT:

Introduction

Hypertension (HTN) and hyperuricaemia (HUA) are chronic metabolic disorders that frequently coexist. Research indicates that HUA prevalence among adolescents and children in mainland China is significantly higher than the global average, with a continuing upward trend. When these conditions occur concomitantly, their detrimental effects on the cardiovascular and cerebrovascular systems far exceed those of either condition alone. The comorbidity of HUA and HTN markedly elevates the risk of adverse cardiovascular and cerebrovascular events, including stroke, ischaemic heart disease, myocardial hypertrophy and left ventricular diastolic dysfunction. In adolescent populations, this comorbidity may also induce subclinical damage such as microangiopathy, premature arterioscl

SUBMITTER: Zhang Z 

PROVIDER: S-EPMC12766805 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature