Emerging genetic diversity and molecular epidemiology of Entamoeba moshkovskii among patients with acute diarrhoea in Northern India.

ABSTRACT:

Background

Entamoeba moshkovskii, a morphologically indistinguishable but genetically distinct species from E. histolytica, has recently emerged as a potential cause of human diarrhoeal disease. Despite its increasing global recognition, its epidemiological role, genetic diversity, and transmission dynamics remain poorly defined, particularly in the Indian subcontinent.

Methods

A prospective study was conducted among 300 hospitalised patients with acute diarrhoea in Northern India to determine the molecular prevalence and phylogenetic diversity of E. moshkovskii. Stool samples were examined microscopically and tested using a species-specific real-time polymerase chain reaction (PCR) assay targeting the 18S rRNA gene. Positive amplicons were sequenced bidirectionally and comp

SUBMITTER: Garg P 

PROVIDER: S-EPMC12766943 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature