Diagnostic BioFire® FilmArray® Pneumonia Panel Plus versus standard microbial culture in bronchiectasis exacerbations.

ABSTRACT:

Background

The diagnostic performance of the BioFire® FilmArray® Pneumonia Panel Plus (FAPP) compared to standard microbial culture (SMC) during bronchiectasis (BE) exacerbations is unknown.

Objective

To compare the microbiological diagnostic performance between FAPP and SMC during BE exacerbations.

Study design and methods

A prospective observational study was conducted in adults with a BE exacerbation at the Hospital Clinic of Barcelona (Spain) June 2020 to April 2022. All sputum samples underwent processing using both the FAPP and SMC (n = 109) but we focused in good quality samples (n = 73).

Results

The FAPP detected pathogens in a higher percentage (n = 64, 88%) compared to SMC (n = 41, 56%). This increase was higher in samples from patients receiving empi

SUBMITTER: Oscanoa-Huaman P 

PROVIDER: S-EPMC12766951 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature