Quantitative EEG and dysautonomia in patients with temporal lobe epilepsy.

ABSTRACT:

Background

The temporal lobe is considered as one of the important higher autonomic centers. It has been suggested that autonomic dysfunction could have a potential role in the pathophysiology of sudden unexpected death of epileptic patients (SUDEP). This study aimed to detect autonomic dysfunction in patients with temporal lobe epilepsy (TLE) using different electrophysiological tests and to correlate them with the SUDEP risk.

Methods

This observational case-control study included 27 TLE patients and 27 age- and gender-matched controls. Detailed history and full clinical examination were performed. Brain MRI were done. Electrophysiological studies in the form of sympathetic skin responses (SSR), heart rate variability (HRV), as well as quantitative electroencephalography (Q

SUBMITTER: Gabr RM 

PROVIDER: S-EPMC12766958 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature