Dietary inflammatory index (DII) and attention deficit hyperactivity disorder: a cross-sectional study in US children and adolescents and Mendelian randomization study.

ABSTRACT:

Background

Diet may impact the risk of attention deficit hyperactivity disorder (ADHD) via altering inflammation. However, no investigations have been conducted to evaluate the relationship between ADHD and the diet's inflammatory potential. The study sought to investigate the relationship between ADHD and the dietary inflammatory index (DII).

Methods

We used data from the cross-sectional National Health and Nutrition Examination Survey 2001-2004 to investigate the relationship between DII and ADHD in 6481 children and adolescents aged 6-19 years. The relationship between ADHD and DII was investigated using weighted logistic regression and restricted cubic spline (RCS). We also explored the potential causal associations between ADHD and 187 types of food preferences using Me

SUBMITTER: Hu J 

PROVIDER: S-EPMC12766964 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature