The Visual Effectiveness and Cost-Effectiveness of Vitrectomy and Membrane Peeling for Primary Idiopathic Epiretinal Membranes (iERMs): A Systematic Review.

ABSTRACT:

Introduction

Primary idiopathic epiretinal membrane (iERM) is a common finding in people aged 50 years or over. It is treated with vitrectomy. There are no definite criteria for when to conduct surgery, and outcomes are variable. This systematic review assessed the effectiveness and cost-effectiveness of vitrectomy surgery for iERM.

Material and methods

Medline, Embase, Cochrane Library and Scopus were searched. Prospective cohort studies, randomised controlled trials (RCTs) and health economics studies published from 2000 to May 2024 were included. The efficacy endpoint was the mean change in best-corrected visual acuity (BCVA) from baseline. Summarising effect estimates were used to synthesise results.

Results

Twelve included studies (11 case series and 1 RCT) met t

SUBMITTER: Doungsong K 

PROVIDER: S-EPMC12767011 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature