Safety Profile of Intraoperative Corneal Debridement in Descemet Membrane Endothelial Keratoplasty (DMEK)-A Retrospective Comparative Study.

ABSTRACT:

Purpose

To investigate the influence of intraoperative corneal debridement on postoperative outcomes in Descemet Membrane Endothelial Keratoplasty (DMEK).

Methods

This retrospective comparative study analyzed 3168 eyes that underwent DMEK between 2012 and 2024. Intraoperative corneal debridement was performed in 215 eyes (6.8%) to improve visualization during the procedure. Survival time analyses with Kaplan-Meier curves and log-rank test and multifactorial Cox regression were conducted to assess the impact of corneal debridement on postoperative graft survival.

Results

Bivariate survival analyses suggested that intraoperative corneal debridement during DMEK may be associated with worse postoperative outcomes in terms of visual acuity, endothelial cell density, graft

SUBMITTER: Arens S 

PROVIDER: S-EPMC12767040 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature