Repression of the <i>fliC</i> gene as an immune evasion strategy in <i>Yersinia ruckeri</i> infection of rainbow trout <i>(Oncorhynchus mykiss)</i>.

ABSTRACT:

Introduction

The virulence of Yersinia ruckeri, the causative agent of enteric redmouth disease in salmonids, is influenced by multiple factors, including flagellar gene expression. This study investigates the role of fliC gene expression in the pathogenicity of Y. ruckeri and its impact on the immune response of infected rainbow trout (Oncorhynchus mykiss).

Material and methods

Using two virulent strains differing in fliC expression, clinical symptoms, mortality rates and key immune parameters were evaluated. Ninety farmed rainbow trout with average body weight of 110.5 ± 24.1 g and average length of 20.7 ± 1.9 cm were used. Allocation was made of 10 fish each to a control group, a low-dose group challenged with one strain, a high-dose gro

SUBMITTER: Schulz P 

PROVIDER: S-EPMC12767157 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature