Development and Evaluation of an Innovative Inflammatory Prognostic Score for Predicting Long-Term Mortality in Patients With Pulmonary Embolism.

ABSTRACT:

Background

Systemic inflammation is closely associated with adverse outcomes in pulmonary embolism (PE). This study aimed to develop and evaluate a novel inflammatory prognostic score (IPS) derived from multiple inflammation-related biomarkers to predict long-term all-cause mortality in patients with acute PE.

Methods

This retrospective cohort study included 1642 patients with confirmed acute PE admitted between January 2016 and January 2024 at the First Affiliated Hospital of Ningbo University and the Affiliated People Hospital of Ningbo University. The primary outcome was all-cause mortality. Follow-up was conducted in January 2025. Fifteen inflammatory biomarkers were analyzed, including C-reactive protein (CRP), white blood cell count (WBC), neutrophil count (NEU), lymph

SUBMITTER: Zhu N 

PROVIDER: S-EPMC12767386 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature