Distribution interactions of the trace elements zinc, copper, and selenium under conditions of their parallel deficiency.

ABSTRACT: Trace elements such as copper, zinc, and selenium are essential micronutrients that play crucial roles in various physiological processes, mainly through their involvement in enzymes and regulatory proteins. A deficiency of any of these elements can impair physiological functions and lead to a range of symptoms. While copper deficiency is rare, e.g., vegans are particularly susceptible to inadequate intake of zinc and selenium. To investigate the effects of multiple simultaneous deficiencies, a feeding study was conducted in adult male and female C57BL/6Jrj mice receiving diets low in copper, zinc, and selenium. This approach enabled us to explore potential interactions between trace elements and to identify organ-specific effects based on their distribution profiles. We observed a substan

SUBMITTER: Lossow K 

PROVIDER: S-EPMC12767715 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature