Lipidomic analysis of Beijing-You chicken breast muscle during growth process reveals lipid changes and key lipid molecules associated with intramuscular fat.

ABSTRACT: This study utilized high-throughput lipidomics to investigate the effects of age (90-150 days, 20-day intervals: D90, D110, D130, D150; 40 birds per age group) on intramuscular fat (IMF) deposition and lipid transformation in the breast muscle of Beijing-You chicken (BYC). A total of 1725 lipid molecules, predominantly categorized as glycerophospholipids (GP), glycerolipids (GL), and sphingolipids (SP), along with 53 lipid subclasses, were identified. Age-dependent IMF increase was mainly associated with triglyceride (TG), cardiolipin (CL) and phosphatidylglycerol (PG) accumulation. Additionally, based on the cutoff criteria of variable importance in projection (VIP) > 1, fold change (FC) > 1.1 or FC < 0.91, and p-value < 0.05, fifty-two lipids were further identified as differentially exp

SUBMITTER: Zhang J 

PROVIDER: S-EPMC12767799 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature